Descripción del prompt

Create a scientific graphical abstract in a 3-panel horizontal layout, clear and minimalistic, suitable for a journal like Advanced Science. Left panel (Injury): Show a brain with a striatal hemorrhage, red hematoma visible, with a small ruptured blood vessel icon below. Label: "Intracerebral Hemorrhage (ICH)". Middle panel (Circadian disruption): Illustrate a hypothalamus with a large clock over it. Clock hands are broken/misaligned. Include a sun/moon icon showing disrupted sleep-wake cycle. Minimal text: "Circadian disruption ↓ Clock gene regulation". Right panel (Exacerbated brain injury): Split vertically. Top (WT + ICH): Moderate immune cell activity (microglia/astrocytes), intact blood-brain barrier (BBB), moderate neuronal loss. Label: "Controlled injury response". Bottom (Clock−/− + ICH): Strong immune cell infiltration, leaky BBB, neuronal apoptosis. Label: "Exaggerated secondary injury". Bottom of panels: A single arrow spanning all panels with text: "Circadian dysregulation amplifies secondary brain injury after ICH". Style: BioRender-like, schematic, colorful but simple, clear, conceptual, journal-ready, no unnecessary details like proteins, RNA-seq, MRI, or time points.