![[chemistry] 你作为一名催化领域的资深科研人员,帮我用催化类国际SCI科研期刊(如Industrial & Engineering Chemistry Research)要求的规范表达将下面中文的科研论文内容用图像的形式表示:OMS-2虽酸含量较低,其酸性位点以弱Lewis酸为主,导致其在反应条件下对NH3的吸附和活化能力较弱。但其易于吸附和氧化NO形成大量的吸附态NxOy,硝酸盐和亚硝](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FsWuA9GXczAROgzlSPVPEt34MDHcPayLJ%2F5f5c2176-2a6f-4a66-8eb5-f4e5d1b5d51d%2F95997d52-badf-4e64-b740-e31291583c0f.png&w=3840&q=75)
你作为一名催化领域的资深科研人员,帮我用催化类国际SCI科研期刊(如Industrial & Engineering Chemistry Research)要求的规范表达将下面中文的科研论文内容用图像的形式表示:OMS-2虽酸含量较低,其酸性位点以弱Lewis酸为主,导致其在反应条件下对NH3的吸附和活化能力较弱。但其易于吸附和氧化NO形成大量的吸附态NxOy,硝酸盐和亚硝酸盐物种。然后在OMS-2上这些硝酸盐物种不容易进一步与NH3发生反应生成产物。但是在Fe-SSZ-13催化剂上这些硝酸盐物种能快速转化成产物分子,因此加速了NH3-SCR反应过程。而Fe-SSZ-13分子筛由于具有强Brønsted酸位和孤立的Fe3+活性位点,能高效吸附活化NH3,并通过L-H机理与吸附态NxOy(如NO⁺,亚硝酸盐)发生快速还原反应[35,52,62]。但吸附在Brønsted酸位上的NH4+较稳定,反应活性较低,导致低温活性较差。而OMS-2催化剂能将NO快速氧化为高反应活性的NO2或N2O4,随后迁移至Fe-SSZ-13组分的强酸性位点上,与NH4+迅速反应[11,63,64],从而实现了复合催化剂的协同催化,拓宽了SCR活性温度窗口。
![[biomedical] Asunto: Ilustración del efecto sinérgico de múltiples fagos combinados con antibióticos para inhibir Vibrio.
Estilo: Ilustración científica concisa, plana o lineal, con azul, gris y verd](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FKHCZxaRZKKInHAddcLDEZF6LE4yVzpdB%2Fa5e38ca8-885a-40ba-a8fa-ea960bb5f012%2F50a31670-94ae-477e-b5bf-f5b64b0f6788.png&w=3840&q=75)
Asunto: Ilustración del efecto sinérgico de múltiples fagos combinados con antibióticos para inhibir Vibrio. Estilo: Ilustración científica concisa, plana o lineal, con azul, gris y verde como colores principales, con etiquetado claro. Composición de la imagen: Izquierda: Diagrama esquemático de la combinación de fagos y antibióticos. Una célula de Vibrio (en forma de bastón, Gram-negativa, con una membrana externa y pared celular) está en el centro. Arriba, dos fagos de diferentes morfologías (como Myoviridae y Podoviridae) se están adsorbiendo e inyectando ADN. A la derecha, moléculas de antibióticos (como un diagrama simplificado de una estructura β-lactámica) se acercan a la pared celular. La pared celular muestra áreas dañadas, lo que sugiere que la lisis por fagos facilita la entrada de antibióticos. Añadir etiquetas de flecha: "Adsorción y lisis por fagos" "Penetración antibiótica mejorada" "Efecto bactericida sinérgico" Derecha: Diagrama esquemático de múltiples fagos en combinación (cóctel de fagos). La misma célula de Vibrio está en el centro, con múltiples sitios receptores etiquetados en la superficie (como OmpU, lipopolisacárido, flagelos). Rodeado por 3-4 fagos de diferentes morfologías, adsorbiéndose a diferentes receptores respectivamente. Utilizar diferentes colores para distinguir los tipos de fagos y etiquetar "Fago A", "Fago B", etc. Se puede añadir un pequeño diagrama debajo para representar la "Fórmula de Optimización Dinámica": mostrando múltiples fagos mezclados en un tubo de ensayo. Diseño general: Las partes izquierda y derecha están separadas por líneas discontinuas, con la parte superior etiquetada: "Diagrama esquemático de la estrategia combinada". Se puede añadir una nota de figura en la parte inferior: "Izquierda: Sinergia fago + antibiótico; Derecha: Estrategia de cóctel de múltiples fagos".
![[ai_system] Este documento describe un enfoque de modelado matemático para analizar y predecir la competitividad de la inteligencia artificial (IA) entre naciones. La idea central implica el uso de mé](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2F2krpfvr5IBM8Ocvk27IT6D8Xg4iyvkGS%2F381cd3d5-8caa-4435-94a2-66f4318089dd%2F59de8451-da0f-498f-83af-5c568ae59428.png&w=3840&q=75)
Este documento describe un enfoque de modelado matemático para analizar y predecir la competitividad de la inteligencia artificial (IA) entre naciones. La idea central implica el uso de métodos estadísticos y aprendizaje automático para evaluar el desarrollo de la IA, pronosticar tendencias futuras y optimizar la asignación de recursos. El análisis se estructura en cuatro preguntas clave: Pregunta 1: Analizar las interacciones e influencias entre 18 indicadores de competitividad de la IA en 25 países durante un período de 5 años. Esto se logrará utilizando matrices de coeficientes de correlación y contribuciones de matrices de componentes. El objetivo es cuantificar las relaciones (sinérgicas o restrictivas) entre estos indicadores e identificar factores comunes que promuevan u obstaculicen el desarrollo de la IA. Pregunta 2: Desarrollar un sistema de evaluación de la competitividad de la IA basado en la matriz de componentes y las contribuciones derivadas en la Pregunta 1. Utilizando datos proyectados para 2025, y asumiendo normalidad, aplicar el análisis de componentes principales (PCA) y potencialmente otros métodos para construir un modelo de puntuación. Después de validar la fiabilidad y validez del modelo, calcular las puntuaciones para cada uno de los 25 países y clasificarlos según su competitividad en IA en 2025. Específicamente, proporcionar clasificaciones para Estados Unidos, China, Reino Unido, Alemania, Corea del Sur, Japón, Francia, Canadá, Emiratos Árabes Unidos e India. Pregunta 3: Cuantificar las tendencias de convergencia o divergencia en la competitividad global de la IA de 2026 a 2035 utilizando el índice de Theil y el coeficiente de variación. Con base en estas tendencias, proporcionar recomendaciones para estrategias de desarrollo sólidas. Además, utilizar modelos de extrapolación de características basados en aprendizaje automático, combinados con el modelo de evaluación de la Pregunta 2, para pronosticar tendencias tanto en los 18 indicadores de competitividad de la IA como en las puntuaciones generales para cada país. Esto informará las recomendaciones con respecto a las futuras necesidades de inversión de recursos y los cambios proyectados en las clasificaciones de competitividad de la IA. Pregunta 4: Emplear un modelo de optimización de programación de objetivos para determinar la estrategia de inversión óptima para que China maximice su competitividad general en IA para 2035, dado un presupuesto de 1 billón de RMB. Esto se basará en el modelo de puntuación de competitividad de la IA de la Pregunta 2 y el modelo de crecimiento de competitividad de la IA de la Pregunta 3. El objetivo es maximizar la puntuación de competitividad de China en 2035 dentro de la restricción presupuestaria especificada. Proporcionar recomendaciones de inversión específicas. En resumen, este es un enfoque integral de modelado matemático para analizar la competitividad de la IA, pronosticar tendencias futuras y optimizar las estrategias de asignación de recursos.
![[biomedical] 研究设计路线
1. 临床研究(阶段Ⅰ)
样本:招募 12-18 岁 SAD 患者 80 例,健康对照 80 例。
靶点筛查:使用 ELISA 或其他检测技术,定量检测血浆中候选靶点(脂联素)及经典炎症因子(IL-6, IL-1β,TNF-α, CRP)水平。
临床与脑功能关联:所有被试完成详细临床评估(儿童社交焦虑量表 (SASC))。进行面部表情识别任务态 fMRI,重](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FAZPMF3Rhkn4oulQKeX4h8aYi7OxUcwki%2F15343b29-d9f2-47ea-950b-544360fdc02c%2F3bb51107-acf3-4322-8e2d-75976df97d89.png&w=3840&q=75)
研究设计路线 1. 临床研究(阶段Ⅰ) 样本:招募 12-18 岁 SAD 患者 80 例,健康对照 80 例。 靶点筛查:使用 ELISA 或其他检测技术,定量检测血浆中候选靶点(脂联素)及经典炎症因子(IL-6, IL-1β,TNF-α, CRP)水平。 临床与脑功能关联:所有被试完成详细临床评估(儿童社交焦虑量表 (SASC))。进行面部表情识别任务态 fMRI,重点分析杏仁核、前额叶对恐惧/中性面孔的反应。分析血浆靶点水平与临床症状、特定脑区激活程度之间的相关性。 2. 动物实验验证(阶段Ⅱ) 模型:采用 C57BL/6J 小鼠,建立慢性社会失败应激模型(诱导稳定的社交回避行为)。 将应激后小鼠随机分为:模型组、药物干预组(如注射脂联素受体激动剂)、阳性药组(如 SSRI)、对照组,干预 2-4周。造模后进行行为学检测:用三箱社交实验评估社交倾向与社交新颖性偏好;用高架十字迷宫、旷场实验:评估一般焦虑与探索行为。检测分子生物学:取前额叶皮层、杏仁核、海马组织,检测神经炎症相关基因表达、小胶质细胞标志物 IBA-1(免疫荧光)。并检测脑组织中与靶点相关的相关通路蛋 白表达。
![[biomedical] 1. 整体构图:
插图以横向构图分为左右两部分,左侧展示宏观应用场景,右侧展示微观交联机制,中间用箭头关联二者。
整体色调采用蓝绿色(代表海藻酸钠)与淡紫色(代表甲基丙烯酸酯基团)为主,搭配橙色(钙离子)与浅黄色(紫外光)点缀。
2. 左侧宏观部分(可注射性与光交联过程):
注射器示意图:
一支透明注射器(针筒标注“可注射前体溶液”)中充满蓝绿色半透明液体,液体](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FRZVJR0Z9AuyCwufiw6TMjJ6sf4hmTyIL%2F6ef285e4-1253-490f-b102-f31b550d6f6d%2Fa85eb1b7-ce66-42e3-ad2f-2b88b1df901e.png&w=3840&q=75)
1. 整体构图: 插图以横向构图分为左右两部分,左侧展示宏观应用场景,右侧展示微观交联机制,中间用箭头关联二者。 整体色调采用蓝绿色(代表海藻酸钠)与淡紫色(代表甲基丙烯酸酯基团)为主,搭配橙色(钙离子)与浅黄色(紫外光)点缀。 2. 左侧宏观部分(可注射性与光交联过程): 注射器示意图: 一支透明注射器(针筒标注“可注射前体溶液”)中充满蓝绿色半透明液体,液体中悬浮微小橙色颗粒(象征钙离子)。 注射器尖端挤出条状凝胶,凝胶表面逐渐由液态转变为固态网络(颜色渐变为半透明绿色)。 紫外光照射场景: 从画面左上角射出一束浅黄色光线(标注“365 nm UV”),光线照射至挤出的凝胶表面。 光束末端泛起柔和的荧光效果,周边点缀光聚合常用的“自由基符号”(·R)。 在光照区域附近标注“LAP光引发剂”并配以分子简式图示。 3. 右侧微观部分(双重交联网络结构): 海藻酸钠主链: 绘制两条波浪状蓝绿色长链,代表GMA改性后的海藻酸钠分子链。 链上间隔悬挂两种功能基团: GMA接枝单元:用紫色六边形表示甲基丙烯酸酯基团,突出其双键结构(C=C)。 羧酸钠单元:用绿色圆环表示,表面带负电荷。 离子交联网络: 橙色小球(标注“Ca²⁺”)与两条链上的羧酸盐基团连接,形成“蛋盒”状交联点。 光交联网络: 在紫外光照射区域,紫色甲基丙烯酸酯基团之间形成共价交联键(用明亮的紫色短链连接,标注“光聚合共价键”)。 部分未反应的C=C双键保留在链上,体现交联度可控。 网络层次标注: 用括号和箭头区分“离子交联区”(以Ca²⁺为中心)和“光交联区”(以紫色共价键为中心)。 背景添加半透明网状图层,象征最终形成的互穿双网络结构。 4. 底部标注与图例: 添加简洁图例说明颜色对应关系: 蓝绿色链:GMA改性海藻酸钠 紫色六边形:甲基丙烯酸酯基团 橙色球:钙离子(Ca²⁺) 浅黄色光束:365 nm紫外光 在右下角添加简式反应式:
![[chemistry] 一张水凝胶合成的示意图,水凝胶基底为甲基丙烯酸缩水甘油酯改性的海藻酸钠,包括海藻酸钠和钙离子交联,甲基丙烯酸缩水甘油酯光交联](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FHD2TMrfzRtTVX8tj37ggwZFIlx7MCErb%2Fb6aad549-44cc-465d-ae7d-869e30982c04%2F7dd04e40-9714-40c4-8ea6-6cb007a4b319.png&w=3840&q=75)
一张水凝胶合成的示意图,水凝胶基底为甲基丙烯酸缩水甘油酯改性的海藻酸钠,包括海藻酸钠和钙离子交联,甲基丙烯酸缩水甘油酯光交联
![[materials] Painel A — Estado inicial (Sample 1)
Duas placas de Petri perfeitamente acopladas.
A amostra em pó (Sample 1 – raw tailings) encontra-se no interior da placa inferior.
Sem ímã, sem movi](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FFuKIrJe0spXScy1Z18usCgr6gpvLkx1f%2Fd8ee6556-6e08-46c2-b6dc-a3987055352a%2F3dd0c641-7bdd-4cf9-b9b8-8f5574082be9.png&w=3840&q=75)
Painel A — Estado inicial (Sample 1) Duas placas de Petri perfeitamente acopladas. A amostra em pó (Sample 1 – raw tailings) encontra-se no interior da placa inferior. Sem ímã, sem movimento. Função: documentar a configuração inicial do sistema. Painel B — Etapa de separação magnética As duas placas permanecem perfeitamente acopladas (sem folga). Um ímã de neodímio (4200 G) é aplicado externamente sobre a superfície da tampa da placa superior. Distância fixa de 3 mm, correspondente exclusivamente à espessura da tampa da placa de Petri. O ímã é deslocado em movimento circular (setas curvas). Não há contato direto entre: o ímã e a amostra; o ímã e a fração magnética. As partículas magneticamente suscetíveis migram e aderem à face interna da tampa da placa superior. Painel C — Resultado final da separação As placas de Petri são separadas fisicamente. A placa superior contém a fração magnética (Sample 3), aderida à sua face interna. A placa inferior contém a fração não magnética (Sample 2). O resultado da separação é visualmente evidente.
![[ai_system] 汇报开场:"各位同事,今天我将汇报R3-RAG与Open AI Co-Scientist的技术整合方案。当前科研辅助系统面临的核心挑战是:传统检索增强生成方法依赖人工设计的固定工作流,缺乏自适应优化能力。"
问题分析:
现有局限:Co-Scientist虽然具备多代理协同优势,但检索策略相对静态
技术机遇:R3-RAG通过强化学习实现了自主的推理-检索策略学习
整合价值:将](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2F0VLFF0qOpp8HSo4kGxZ6WaTGh6OocIiK%2Fc309356e-8747-43df-9f8c-2f46cafd7571%2Fcf1a310b-650c-4a01-87bf-5da6d141e794.png&w=3840&q=75)
汇报开场:"各位同事,今天我将汇报R3-RAG与Open AI Co-Scientist的技术整合方案。当前科研辅助系统面临的核心挑战是:传统检索增强生成方法依赖人工设计的固定工作流,缺乏自适应优化能力。" 问题分析: 现有局限:Co-Scientist虽然具备多代理协同优势,但检索策略相对静态 技术机遇:R3-RAG通过强化学习实现了自主的推理-检索策略学习 整合价值:将R3-RAG的智能检索能力注入Co-Scientist框架,提升科研假设生成质量 1.2 汇报结构概览 本次汇报将分为四个部分: 架构设计:整体整合方案与技术路线 核心实现:关键组件与算法细节 实施计划:阶段化推进策略 预期成效:性能评估与风险控制 2. 技术架构深度解析 2.1 整体架构设计理念 分层融合策略:采用"检索层增强-智能体层改造-训练层集成"的三层架构 架构示意图说明: 用户输入 ↓ [R3-RAG增强检索层] - 动态路由+多跳检索 ↓ [Co-Scientist智能体层] - 生成、反思、排名代理增强 ↓ [强化学习训练层] - OpenRLHF策略优化 ↓ 优化输出 + 策略更新 2.2 数据流与控制流设计 工作流程: 智能检索:基于查询复杂度的动态路由(单跳/多跳) 假设生成:检索增强的上下文感知生成 双重评估:结果奖励+过程奖励的综合评分 策略优化:周期性的强化学习训练 3. 核心组件技术实现 3.1 智能检索服务(技术亮点) 动态检索路由机制: def dynamic_retrieval(query, complexity_threshold=0.7): complexity = assess_complexity(query) # 语义复杂度分析 if complexity > threshold: return multi_hop_retrieval(query) # 复杂问题:3跳递归检索 else: return single_retrieval(query) # 简单问题:单次检索 多跳检索实现: 跳数控制:最大3跳,防止无限递归 混合检索:BGE密集检索 + BM25稀疏检索 上下文演进:基于前跳结果深化查询语义 3.2 生成代理增强(创新点) 检索增强的提示工程: 传统提示:[研究问题] → LLM生成 增强提示:[研究问题] + [相关文献] + [现有假设] → LLM生成 元数据丰富化: 记录检索跳数、复杂度评分、支持文档 提供假设生成过程的可解释性 支持后续奖励计算和策略优化 3.3 双重奖励系统(核心技术) 奖励计算框架: 总奖励 = 0.6 × 结果奖励 + 0.4 × 过程奖励 结果奖励维度: 新颖性(40%):与已有研究的区分度 可行性(30%):技术实现路径合理性 科学性(30%):理论基础牢固程度 过程奖励机制: 文档相关性:假设与支持文献的语义相似度 检索效率:单位跳数获得的有效信息量 证据质量:引用文献的权威性和时效性 3.4 强化学习训练闭环 训练数据自动化收集: 每个假设的生成全过程记录 检索策略、奖励分数、最终效果 最小样本量:10个高质量交互轨迹 策略热更新机制: 训练频率:每5个运行周期 更新方式:策略参数热替换 回滚保障:异常检测与自动恢复 根据以上信息,画一个科研绘图风格的系统架构图
![[biomedical] ABSTRACT
Background: Obstructive sleep apnea (OSA) is a common but underdiagnosed health condition among patients with atrial fibrillation (AFib) and may be associated with adverse cardi](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FqLkKQr33Kqhc5aVD7dxLAnLwsXJvfG9R%2F6ea3ea9a-cf89-4bb2-83d4-aa629338fd30%2F179f871a-cd6d-4b27-8143-9479c8abc2f2.png&w=3840&q=75)
ABSTRACT Background: Obstructive sleep apnea (OSA) is a common but underdiagnosed health condition among patients with atrial fibrillation (AFib) and may be associated with adverse cardiovascular outcomes. Objective: We sought to evaluate the association between OSA and clinical outcomes in a large, propensity-matched cohort of adults with AFib. Methods: From the TriNetX network we identified adults with AFib with (AFib+OSA) and without OSA (AFib-OSA). Cohorts were 1:1 propensity-score matched (n=174254 each) for demographics, comorbidities, medications and laboratory parameters. The outcomes of interest were all-cause mortality, ischemic stroke, heart-failure (HF) exacerbation, all-cause hospitalization, repeat cardioversion, acute coronary syndrome or pulmonary embolism (ACS/PE), and major bleeding at a median follow-up of 365 days. Results: After matching, AFib+OSA group had a higher risk of all-cause mortality (HR:1.20, 95% CI:1.10-1.30, p<0.001, respectively), stroke (OR:1.90, 95% CI:1.72-2.09, p<0.001, respectively), HF exacerbation (OR:1.22, 95% CI:1.19-1.24, p<0.001, respectively), all-cause hospitalization (OR:1.17, 95% CI:1.15-1.19, p<0.001, respectively), and repeat cardioversion (OR:1.28, 95% CI:1.25-1.32, p<0.001, respectively). The incidence of ACS/PE and major bleeding were comparable between groups. At 12 months, AFib-OSA group had a higher probability of event free survival compared to patients with AFib+OSA (Hazard ratio: 1.20, 95% CI:1.10-1.30; log-rank test chi-square=19.31; p<0.001). Conclusion: The presence of OSA is associated with higher all-cause mortality and stroke in patients with AFib compared to those without OSA. Additionally, HF exacerbations, all-cause hospitalizations, and the need for repeat cardioversion were more frequent, whereas major bleeding and vascular thrombotic events including ACS and PE, were not increased. Keywords: Atrial fibrillation, cardiovascular outcomes, mortality, obstructive sleep apnea, stroke
![[biomedical] Create a graphical abstract in three panels (left to right).
Left: a generic quinone–1,2,3‑triazole scaffold (benzoquinone + 1,2,3‑triazole, R1/R2) with text ‘18 quinone‑1,2,3‑triazole de](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2F2AsG6TXrWDwBfQIVyl9i3ptkNtfWwfPZ%2F6108ce9b-ca25-4cd1-8afe-f45e3e21c092%2F6ded1fc6-9540-416e-8037-5ba8bad9fd96.png&w=3840&q=75)
Create a graphical abstract in three panels (left to right). Left: a generic quinone–1,2,3‑triazole scaffold (benzoquinone + 1,2,3‑triazole, R1/R2) with text ‘18 quinone‑1,2,3‑triazole derivatives’, arrow to a colon cancer cell labeled ‘HCT116 cytotoxicity (IC50 < 0.6 – > 0.9 µM)’, arrow text ‘In vitro activity’. Middle: colon silhouette with protein icons labeled PARP1, AKT1, TRAF2, and ‘Other CRC targets (n = 15)’, arrow from scaffold labeled ‘Molecular docking (18 targets)’, small 2‑color heatmap with legend ‘High binding (C01, C04–C06, C16)’ and ‘Low binding (e.g., C07)’, PARP1 highlighted with text ‘Best binding & IC50 correlation’. Right: zoom on ‘PARP1 binding site’ with one ligand ‘C16 (representative)’ showing hydrogen bonds (GLU13 / ASP82 / LYS85 / ASP141), π‑stacking (TYR16 / PHE76), halogen bond (GLU9); below, simple RMSD plot ‘Stable MD complex (100–200 ns)’ and bar icon ‘MM‑PBSA ΔG_bind’ for C01, C04, C05, C06, C16 with note ‘More negative → stronger binding; trend matches HCT116 IC50 (strong < 0.6 µM > moderate > weak)’. Use blue for compounds, orange for proteins, green for PARP1 focus
![[biomedical] erstelle eine visual abstract für eine wissenschaftliche zeitschrift aus meinem abstrakt: Abstract
Aims:
We evaluated safety and efficacy of very high-power short-duration (vHPSD) temper](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2F1uZzzLX3CyHGzrGvIqaviGhaXZFH93NZ%2Fd7f450d5-8cc0-4c03-bcb5-4141277bc3a3%2Fc25b5063-448d-402f-9b41-b618c495678f.png&w=3840&q=75)
erstelle eine visual abstract für eine wissenschaftliche zeitschrift aus meinem abstrakt: Abstract Aims: We evaluated safety and efficacy of very high-power short-duration (vHPSD) temperature-controlled radiofrequency (RF) cavotricuspid isthmus (CTI) ablation with 90 watts over 4 seconds (90W/4s) for typical atrial flutter (AFL) in comparison to conventional contact-force (CF) ablation-index (AI) guided ablation. Background: Catheter ablation for AFL treatment provides effective and durable CTI block associated with encouraging clinical outcome. Very HPSD ablation with 90W/4s aims for an effective, safe, and faster procedures. It’s role on long-term outcomes after CTI ablation remains insufficiently investigated. Methods: Patients with symptomatic typical AFL were enrolled. Fifty consecutive patients underwent vHPSD based CTI ablation (vHPSD-group) and were compared with 50 consecutive patients treated with conventional AI-guided CF-sensing catheters (AI-group). Results: All CTIs were successfully blocked using either method. Median RF applications and RF times in the vHPSD-group and AI-group were 36 [IQR 26;47] versus 18 [IQR 12;26], p<0.001 and 142 sec [IQR 105;189 sec] versus 574 [IQR 401;983], p<0.001, respectively. No differences in periprocedural complications were observed. Recurrence of AFL after 12 months was low with no significant differences between groups (8 % vs. 2 %, p=0.169). In patients with re-ablation there was no difference in durably blocked CTIs between both groups (75% vHPSD-group versus 67% AI-group, p=0.809). Conclusions: The vHPSD (90W/4s) ablation mode provides a safe and effective approach for CTI ablation with the added benefit of a shorter RF application time in comparison to AI-guided ablation. Periprocedural event rates, acute and durable CTI block rates as well as long-term rhythm outcome are comparable between both ablation strategies.
![[environment] 一张UASB实验装置图。实验装置主要包括以下部分:
(1) 进水系统:由进水瓶、气袋、蠕动泵(BT100-1F)和进液管组成;
(2) UASB反应单元:包含活性污泥、模拟废水、气袋、磁力搅拌器和保温装置;
(3) 出水系统:由产水管、产水瓶及气袋构成。](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FmAPXjhdw14r40nmzWtN22lVLUrH2mv3N%2F30743a21-a148-4408-b973-9d3979e60cc4%2F2a69f573-4fa0-4002-bbbd-159bc995e40f.png&w=3840&q=75)
一张UASB实验装置图。实验装置主要包括以下部分: (1) 进水系统:由进水瓶、气袋、蠕动泵(BT100-1F)和进液管组成; (2) UASB反应单元:包含活性污泥、模拟废水、气袋、磁力搅拌器和保温装置; (3) 出水系统:由产水管、产水瓶及气袋构成。
![[biomedical] PLASMIDS](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FbUii5gGTaq96pSFWpSZzUzaef0wJ2hxf%2F5082aa45-2558-486e-87a0-67c33b2d4dde%2F4ac502a6-7e16-4a36-b036-df6ed4d65e78.png&w=3840&q=75)
PLASMIDS
![[chemistry] Rizomas de Cimicifuga heracleifolia Komar. con raicillas removidas y rizomas de Cimicifuga heracleifolia Komar. con raicillas chamuscadas se secaron y pulverizaron, luego se pasaron a trav](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FJoefOmszrIKsmYfL4KtC0PPhiJHP3j0i%2F977ddd2b-0562-4884-af29-21b2f401c8a9%2F63f23fab-791a-4dbf-bbe3-ef41f3d65538.png&w=3840&q=75)
Rizomas de Cimicifuga heracleifolia Komar. con raicillas removidas y rizomas de Cimicifuga heracleifolia Komar. con raicillas chamuscadas se secaron y pulverizaron, luego se pasaron a través de un tamiz No. 2. 400.00g del polvo de rizomas con raicillas removidas y 400.00g del polvo de rizomas con raicillas chamuscadas se extrajeron por reflujo tres veces con 15 veces el volumen de etanol al 70% durante 2 horas cada vez. Los extractos se combinaron, concentraron y liofilizaron para obtener el extracto etanólico de rizomas con raicillas removidas y el extracto etanólico de rizomas con raicillas chamuscadas.
![[biomedical] 一张细胞图,TCA循环,电子传递链,反硝化过程。图中需要出现上述生物过程中出现的酶及其他复合物或者其他物质,包括电子的流动,反硝化酶的呈现。上述生物过程的物质转化。](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FBQQwtebEue6fKFfbba6uZQUK5BOOaMFg%2F3e5b7302-f6b3-4cd5-b9cf-a743966373a6%2F3d072cd4-8bdb-498b-ab68-f9b34280175b.png&w=3840&q=75)
一张细胞图,TCA循环,电子传递链,反硝化过程。图中需要出现上述生物过程中出现的酶及其他复合物或者其他物质,包括电子的流动,反硝化酶的呈现。上述生物过程的物质转化。
![[biomedical] Diagrama de sección coronal del recto inferior.](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FxlJRK8U1iCh9l3MPOXw1uEnuRkykMHXd%2F12eabd0c-2b80-4cb3-bda5-2348a6a3bb87%2F7aea5af5-8c9e-4748-b4dc-a359e7e819cb.png&w=3840&q=75)
Diagrama de sección coronal del recto inferior.
![[ai_system] Generate a publication-quality mechanism schematic (clean vector style, 2D plane) for a truck–multi-drone cooperative parcel delivery problem. Place one Depot and multiple scattered custom](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FFLY2tPMrNsnHMMfFR83X1XuhwAAEYfnf%2F127052ca-b675-4d14-8d1b-9d59a39432ad%2F1deed93f-9987-4cb8-9228-7cfb588db0c9.png&w=3840&q=75)
Generate a publication-quality mechanism schematic (clean vector style, 2D plane) for a truck–multi-drone cooperative parcel delivery problem. Place one Depot and multiple scattered customer nodes on a map. Customer types (must be explicit and shown in a legend): Type 1 (drone-eligible) customers: can be served by either the truck or a drone. Type 2 (truck-only, heavy parcel) customers: can be served only by the truck (drones are not allowed to visit Type 2). Truck operations: A single truck carries a homogeneous fleet of Nd drones and all parcels. The truck departs from the depot, visits some customers sequentially, delivers parcels at truck-visited customers, and returns to the depot. Draw the truck route as a solid line with direction arrows; label a few visited nodes as “Truck served”. Mobile satellite concept (critical detail): A mobile satellite is not a separate facility; it is a customer node (either Type 1 or Type 2) on the truck route. Only when the truck stops at a customer node and launches/retrieves drones, that customer node is called a “mobile satellite”. Visually mark such nodes with a special ring/halo and label “Mobile satellite (customer node + truck waiting)”. Drone operations and constraints: Drones may launch only from the truck at a mobile-satellite customer node, serve one or multiple Type 1 customers during a sortie (multi-stop allowed), and then return to the same mobile-satellite node. The truck waits at the mobile-satellite customer node until all dispatched drones return, then continues its route. Draw drone flight paths as dashed green arrows forming outbound and return legs (or dashed loops), and label one example as “multi-stop drone sortie: Type 1 → Type 1 → return”. Add a small note: “Battery swapped instantly upon return; swap time negligible.” Service rule: each customer is served exactly once by either the truck (Type 1 or Type 2) or a drone (Type 1 only). Use minimal text, high contrast, and a clear legend. Inc
![[biomedical] 我的论文中的一个汇总图,总标题是
Cognitive Dysfunction and Brain–Cognition Coupling in MDD and BD
左上:Objective Cognition
Substantial deficits in both MDD and BD, with heterogeneity
右上:Brain–Cognition](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FEGOMNOH7JwFiya3xC8Ji2cOkfvaZtywa%2F8eccf211-325e-49fd-826c-c38a22dbdb6e%2Fb7b902c6-a169-4ea2-8525-92da7b6cfc2b.png&w=3840&q=75)
我的论文中的一个汇总图,总标题是 Cognitive Dysfunction and Brain–Cognition Coupling in MDD and BD 左上:Objective Cognition Substantial deficits in both MDD and BD, with heterogeneity 右上:Brain–Cognition Coupling MDD: Negative coupling BD: Positive coupling 左下:Subjective vs Objective Subjective cognition tracks symptom burden 右下:Clinical Relevance Subjective cognition best predicts functioning
![[biomedical] Scientific illustration, correct simplified internal anatomy of Common Crane (Grus grus). Semi‑transparent silhouette showing lungs, heart, air sacs, liver, stomach, intestines. Vector‑li](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2Fl98vUmhcAChoMlRhZi3S091oAAW5Mupg%2Fd9b467f5-6c62-428d-9b05-25fe5c07b4ed%2Fb185a46b-c790-4f3c-ae19-5d49b49728a2.png&w=3840&q=75)
Scientific illustration, correct simplified internal anatomy of Common Crane (Grus grus). Semi‑transparent silhouette showing lungs, heart, air sacs, liver, stomach, intestines. Vector‑like style. Transparent background.
![[biomedical] Una ilustración científica simplificada que representa la anatomía interna de un oso pardo (Ursus arctos). Una silueta semitransparente revela los pulmones, el corazón, el hígado, el estó](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FKSIi0Vj2eDYxTWaDQxbszttnYzsDyxFd%2F116c85f4-77a3-4321-91af-24f839a8fa33%2F329cba6b-ce4a-45bc-9343-5f6d05c0d994.png&w=3840&q=75)
Una ilustración científica simplificada que representa la anatomía interna de un oso pardo (Ursus arctos). Una silueta semitransparente revela los pulmones, el corazón, el hígado, el estómago y los intestinos. El estilo es vectorial y el fondo es transparente.
![[biomedical] Extern anatomi
Scientific illustration, correct external anatomy of Red Fox (Vulpes vulpes). Vector‑like style, clean linework, flat natural colors. Labeled body parts. Full body, centere](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2F1qmpvjrmaW1aS8ZRlWpB1TOW1OkHqxBS%2Fc48a0a4e-782d-4551-bbaf-87ca65a95b66%2F9ce57ef7-8e67-435a-a3cd-057e51c5a213.png&w=3840&q=75)
Extern anatomi Scientific illustration, correct external anatomy of Red Fox (Vulpes vulpes). Vector‑like style, clean linework, flat natural colors. Labeled body parts. Full body, centered. Transparent background.
![[chemistry] synthesis of ternary composite through ex-situ method. take 100ml distilled water and add 0.8g GO in it, ultrasonic it for 1 hour at 30 degrees. take 100ml distilled water and add 1.1g zn](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2F1LcliWTZaJsBmGkqfgJ7jyK7RAIY4OiN%2F44ae28ce-59ee-476e-bb16-7402fe5d95c0%2Ff78e80c7-e61a-47a2-a35d-78e6ee4b0210.png&w=3840&q=75)
synthesis of ternary composite through ex-situ method. take 100ml distilled water and add 0.8g GO in it, ultrasonic it for 1 hour at 30 degrees. take 100ml distilled water and add 1.1g zn mof in it and ultrasonic at 30 degrees for 1 hour. take separate beaker of 50 ml distilled water and add 1.1g Sr2NiMoO6 and ultrasonic at 30 degrees for 30 mints.. after completing this process, mix double perovskite into GO and zn mof and stirr on hotplate at 40 degrees for 1 hour then again ultrasonic for 30 mints. pour into autoclave and place in oven at 180 degrees for 12 hours. then, centrifuge three times with distilled water, heat further in an oven and for dry and calcinate at 250 degrees for 1 hour
![[chemistry] In the first place, 7g zinc nitrate hexahydrate and the 2.5 g benzene-1,3-dicarboxylic acid which acts as an organic linker, were placed separately in two beakers. Then, the solvent compos](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FlWaMizPUxMRnoobpXcSqJmBvPLiozmF3%2F6fd5aa50-413b-40f7-8b45-e62bfefd50a9%2F4e0c9734-3146-48ac-9272-6333d43de2a1.png&w=3840&q=75)
In the first place, 7g zinc nitrate hexahydrate and the 2.5 g benzene-1,3-dicarboxylic acid which acts as an organic linker, were placed separately in two beakers. Then, the solvent composed of 30ml deionized water and 10ml ethanol was gradually added to the two beakers to facilitate the dissolution of the chemicals. The solutions were stirred at a moderate temperature of 50 degrees to ensure the zinc nitrate completely dissolved. Afterwards, the solution containing the organic linker was combined with the solution containing the zinc nitrate, and the solution were stirred again at 50 degrees for half an hour. The main purpose of the mixing was to allow the interaction between the zinc ions and the organic linkers and begin forming the framework. Then, the solution was then transferred into an oven and heated at 150 degrees for 8 hours. After, heating yellow solid particles appeared in the solution. The liquid on the top was discarded, and the Zinc-MOF particles were washed several times with deionized water and ethanol to get rid of any impurities. In the end, the purified Zinc-based nanoparticles were dried in the oven at 150 degrees for 2 hours.
![[biomedical] rotenone induced Parkinson disease rat model
treatment drug is 2,2Np 1,3TZD 4-CA
behavioral analysis
biochemical analysis
iron analysis
histopathology of brain tissues](/_next/image?url=https%3A%2F%2Fpub-8c0ddfa5c0454d40822bc9944fe6f303.r2.dev%2Fai-drawings%2FOCknWFEbua61b1srOaWXdqIQtQfaBPgL%2F524f4045-3261-4633-9ec6-1d5be57e5786%2Fc754aa69-d676-4873-b335-85d5f6ed4146.png&w=3840&q=75)
rotenone induced Parkinson disease rat model treatment drug is 2,2Np 1,3TZD 4-CA behavioral analysis biochemical analysis iron analysis histopathology of brain tissues