Prompt Description

Transform the core mechanism description of CORO1A in OA that you provided into clear and specific AI drawing instructions as follows. You can use this text directly for AI image generation tools. ### **AI Drawing Instructions** **1. Core Theme and Style** * **Theme**: Generate a **scientific mechanism diagram** illustrating the “CORO1A-mediated chondrocyte-immune cell vicious cycle in osteoarthritis (OA).” * **Style**: **Modern flat vector illustration style**, similar to mechanism diagrams in top academic journals (such as *Cell*, *Nature*). Requires simple lines, clear color blocks, and a sense of technology, avoiding overly complex realistic rendering. * **Composition**: Use a **circular layout** to visually represent the “cycle.” The main elements are arranged around a central ring, with arrows clearly indicating the direction of action. * **Color Scheme**: * **Chondrocytes/Cartilage-related**: Use **blue tones** (such as light blue, dark blue). * **Immune cells/Inflammation-related**: Use **red/orange tones** (such as warm red, orange-yellow). * **Core molecule CORO1A**: Use a **prominent, high-contrast color**, such as **bright yellow or magenta**, and make it glow or highlight in the image. * **Background and Arrows**: Use a light gray or white background, with dark gray or black arrows. **2. Description of Screen Elements and Layout (in cyclical order)** * **Starting Point (12 o'clock direction)**: * Draw a set of **downward-projecting “signal arrow rain” icons** symbolizing “chronic inflammatory signals” (such as IL-1β, TNF-α). * Below the arrow rain, draw a **normal chondrocyte icon** (shape can be simplified to a circle or ellipse). * **Step 1: Chondrocyte State Transition (left side)**: * Draw an arrow from the normal chondrocyte, pointing to two **new cell icons**. * The first icon is labeled **“InfC”** (inflammatory chondrocyte), and a small flame icon can be added next to the cell to indicate inflammation. * The second icon is labeled **“ProC”** (proliferative chondrocyte), and a dividing arrow icon can be added next to the cell to indicate proliferation. * Inside these two cells, draw a **significantly glowing, enlarged “CORO1A” molecule model** (can be represented by a simple ball-and-stick model or double-sphere model) to emphasize its high expression. * **Step 2: Dual Role of CORO1A (bottom left to bottom right)**: * Draw **two branching arrows** from the highlighted CORO1A molecule: 1.