
APPROVED This document outlines the creation of a mechanism-style scientific figure that summarizes the development of minimum requirements for longitudinal flow cytometry studies. The figure should employ a clean, Nature/Cell-style schematic with vector icons, clear arrows, feedback loops, and minimal text, with the layout flowing from left to right. **TITLE:** Mechanism for Developing Minimum Requirements for Longitudinal Flow Cytometry Studies **LEFT PANEL — INPUT VARIABILITY SOURCES:** A cluster of icons representing: * Flow cytometer * Antibody vials / reagents * Operators / technicians * Multi-site instrument locations * High-parameter data plots Labels: * Instrument drift * Operator variability * Antibody/reagent lot differences * Multi-instrument / multi-site heterogeneity * High-dimensional panels * Complex analysis pipelines Arrows from all sources converge into a central problem node: Node label: “Need for Standardized Guidance” **CENTER PANEL — ITERATIVE COMMUNITY CONSENSUS MECHANISM:** Display a sequential cascade of four nodes with arrows and one feedback loop:
APPROVED This is a professional, rational, and concise one-p...