Prompt Description

Please generate a schematic diagram of a cell that overexpresses the TNFR2 receptor on its surface. Inside the cell, there are luciferase reporter molecules linked to DNA sequences that can be bound by the NF-κB protein. When a drug binds to the TNFR2 receptor, the intracellular NF-κB signaling pathway is activated. The NF-κB protein will then enter the nucleus and bind to the DNA sequence, thereby initiating the expression of the downstream luciferase gene. Ultimately, the activity of NF-κB is quantified by measuring the fluorescence intensity.