Prompt Description

Figure 2: Key Clinical Evidence in CKRT Dosing and Outcomes Overall Layout: Total dimensions: 850 × 500 px Panel A: x=30, y=55, width 320, height 190 (Dose-Mortality) ⚠️ Revised to binary comparison Panel B: x=365, y=55, width 220, height 190 (Downtime) ⚠️ Revised Panel C: x=600, y=55, width 220, height 190 (NUF rate bar chart) Panel D: x=30, y=270, width 440, height 95 (KDIGO dose scale) Panel E: x=485, y=270, width 335, height 95 (RCA vs. Heparin) Panel A: Dose-Mortality ⚠️ Revised to Binary Forest Plot Important: The Okamoto 2024 study only performed a binary comparison and does not have HR data for multiple dose groups. Design: Forest plot style binary comparison Reference Lines: - HR=1 vertical dashed line: x=200, from y=85 to y=180 - HR scale axis: x=100→300, scale 0.5, 1.0, 1.5, 2.0, 2.5 Above-median group (≥13.2 mL/kg/h): - Label: '≥13.2 mL/kg/h (Above median)', y=115-127 - Data point: Center (200, 120), fill #27ae60 - Annotation: 'Reference' Below-median group (<13.2 mL/kg/h): - Label: '<13.2 mL/kg/h (Below median)', y=155-167 - Error line: HR 1.73 (95% CI 1.19-2.51) - Calculation: With x=200 as HR=1, every 0.5 HR = 50px - HR 1.19 → x=219 - HR 1.73 → x=273 (center position) - HR 2.51 → x=351 (truncated display to x=300) - Horizontal line: x=219 → x=300, color #c0392b 2px - Data point: Center (273, 160), radius 6, fill #c0392b - Annotation: 'HR 1.73 (1.19-2.51)' Key Findings Box: - Location: x=50, y